Thursday, October 31, 2019

Illiad and Odyseey Greek Mythology about the Soul Essay

Illiad and Odyseey Greek Mythology about the Soul - Essay Example The underworld was ruled by Hades, and all souls after physical death went there. Greek religious beliefs were not written down in parchments but were orally passed on from one generation to another. In every culture, epical stories were created, basing on religious beliefs, and exchanged through word of mouth so that the thoughts and beliefs took deep roots in society. While philosophy was hard for the average human being to understand, fictionalized accounts were easily comprehended. Heroic stories had the power to pass on values and moral to people rather than scripts intended to preach religion. Narratives based on adventures of brave and idealistic protagonists, therefore, became popular among masses and the authors interlaced such sagas with religious and philosophical thoughts in a manner accessible to ordinary people. Thus, Iliad and Odyssey, the two epics by Homer, have a strong influence not only on Greek culture but also on their religion. Homer’s â€Å"Odyssey† is an account of Odysseus’ return to Ithaca from the Trojan War. It narrates his adventures and how he overcame the wrath of Poseidon, with the help and blessings of Goddess Athene, daughter of Zeus. Odyssey concentrates on the happenings in Odysseus’ native land, Ithaca during a twenty year period when he was away from his motherland, and the tribulations suffered by his faithful wife Penelope and son Telemachus. Finally, after a long and arduous struggle, Odysseus returns to his land, with the help of the goddess Athene, and is reunited with his wife and son. He also succeeds in killing all the suitors who wanted to marry Penelope during his long absence from Ithaca. As was the contemporary practice prevalent during that time the dead were not buried but cremated. The practice of building â€Å"a mould with all the proper funeral rites† was also practiced. (Homer, 1991. p.12, line 293).  

Tuesday, October 29, 2019

Media Analysis on Simon Dalby’s Challenging Carboniferous Capitalism Essay Example for Free

Media Analysis on Simon Dalby’s Challenging Carboniferous Capitalism Essay The main concept expressed in Simon Dalby’s Challenging Carboniferous Capitalism is about capitalist economics. It stated the different issues and concerns related to how capitalist economics work. The article expressed the relevance of knowing the connection of the current situation of the environment to the different decisions made in the political economy that could lead to social change. Describing the process of how capitalist economics works, one can see definite manifestations of the improper distribution of resources that is now also slowly depleting despite the growing demand. The scope of the problem is also sufficiently explained making one able to picture a world that will later lead to distraction if not given due attention soon. The article greatly gave emphasis to the environmental problems and catastrophes resulted from political movement that is basing nominal figures of growth rather than understanding nature and its role in every people’s lives. It is greatly connected to the issue of consumerism. The article is putting forward what consumerism has done to our environment and to people that are economically or financially challenged. It is magnifying on the inequality present because of selfishness and greed. According to Anup Shah’s article Consumption and Consumerism, the impacts of consumerism both positive and negative are very significant to all aspects of people’s lives and the planet. He specifically pointed out the imbalance of the distribution of benefits to people. As a capitalist economy is fed by consumerism, both these concepts are seen together in the picture. Dalby cited different developments in how environmentalists today assert their cause in saving mother Earth. He also mentioned the nasty ways people try to meet with the growing demand for material needs both necessity and luxury, the benefit of reducing consumerism and seeing the value of one’s action as it affects everyone. In the whole, Dalby expressed abhorrence to the reality today that to instill the value of life to people one is to base their arguments to highly technical matters as trading quotas and industrial standards just to make corporations understand that they are trying to destroy the environment in making money. The highlighted issue in Dalby’s article greatly pictures the situation of our times today, known and unknown to many. It is known because there have been many environmental catastrophes happening for the past ten years such as the hurricane Katrina, the tsunami in Thailand, the storm Ondoy in the Philippines, and many others. But it is unknown still to many because people never see consumerism and a capitalist economic system are one of the culprits to these disasters. As mentioned, the Kyoto Protocol and other climate change negotiations have failed to encourage all nations to act on their part in saving mother Earth. One of them was China which is now reported as the second largest economic power passing Japan (The New York Times, 16 Aug 2010). In the article, it was said that China â€Å"is reluctant to play a greater role in the debate over climate change or how to slow the growth of greenhouse gases,† though they are currently instilling an ambitious program to cut energy it uses on economic output by 20 percent by the end of 2010. This initiative is yet to be seen. The concept, capitalist economy as discussed in Challenging Carboniferous Capitalism is not really defining much of the top players in the issue which I believe is the capitalists. It greatly centered on the effects of capitalist economy to what people value best in life—which is now more on materialism. Because of the author’s emphasis, he connected other concepts as consumerism and materialism to further his explanation. The point that is seen relevant starting with this concept is on how the policy making of government and institutions are influenced by capitalist economic system because the money is there and the capitalists are the ones seen in the spotlight when talking about a country’s economic standing. The concept can not put directly into account the individuals, which are the consumers that support it. The question that one can raise in putting this concept affront in this article is that, why not directly mention the capitalists need to see the value of life rather than directing to the consumers? Bibliography http://finance. yahoo. com/news/China-Passes-Japan-as-nytimes-2766831302. html? x=0. v=1 China passes Japan as second-largest economy, 2010. 16 Aug 2010. 16 Aug 2010. Shah, Anup. â€Å"Consumption and Consumerism. † http://www. globalissues. org/issue/235/consumption-and-consumerism. Global issues, 03 September 2008. 16 August 2010,

Sunday, October 27, 2019

The Psychology Of Team Sports

The Psychology Of Team Sports Hardy and Grace, (1997) outlined the importance of team building research in sport when they suggested whether a team is successful or not is frequently attributed to the effectiveness of their teamwork. To develop the effective team many team building programs attempt to increase cohesion amongst a group as team cohesion can affect performance (Eys et al, 2005). Different areas of group dynamics can be used to increase team cohesion, this section of the report will focus on the research conducted on leadership, role ambiguity and goal setting. Leadership is an important component for developing cohesion in sports teams (Carron et al, 2005). It has been suggested that effective leadership is a vital contributor to member satisfaction (Reimer Chellandurai, 1995). Leadership behaviours and styles adopted can have a big impact on team cohesion and subsequent performance. (Carron et al. 2005) An early study, investigating the relationship between (the coaches) leadership behaviours and team cohesion within sports teams, found adopting a democratic style produced higher levels of task cohesion (Lee et al. 1993). In addition, a variety of studies reported that an increase in social support behaviour increased task cohesion (Lee et al. 1993, Westre Weiss, 1991; Riemar Chellandurai, 1995). One study, Riemar Chellandurai, (1995) went further and examined the leadership behaviours preferred and perceived by players depending on their position. They found defensive athletes perceived and preferred higher levels of social support and democratic and autocratic styles then the offensive athletes. They also found member satisfaction was greatly influenced by social support. More recent research has tended to focus on the role of the athlete as a leader within the team, for example, the captain. Research has suggested athlete leaders are in fact better than coaches at administering leadership behaviours, such as; a democratic decision making style and social support (Loughead and Hardy, 2005). Whats more, further research has been conducted to assess different types of athlete leadership. For example, Loughead et al, (2006) discovered two types of leader within a sports team; a team captain and a peer leader (supplies leadership to at least 2 team members). In addition, Eys et al, (2007) investigated how 218 athletes perceived the athlete leader distributions within their sports teams. Their results suggest that members of a team are more satisfied when 3 leadership roles (social, task, external) are performed to the same extent regardless of how many are leaders present within the team. Carron et al, (2005) identified individual clarification of role responsibilities to be one of the most important factors in sport. The vast majority of research on role states in team sports has been on role ambiguity (role clarity) and its relation to performance using the conceptual model proposed by Beauchamp et al, (2002). The effect role ambiguity had on both task cohesion and task self efficacy was investigated by Eys Carron (2001). They concluded that members within basketball teams who were unsure of their role responsibilities, reported lower levels of attraction towards the team and felt their team was less unified in their task approach. Another study, Eys et al, (2003) demonstrated that team members perceptions of role ambiguity decreased throughout a competitive season. Additionally, although perceptions of role ambiguity are individual, members of a team could share the same beliefs. Finally, new editions to the team are more likely to perceive role ambiguity compared to experienced members of the team at the start of the season. Nevertheless, as the authors suggested, the results of this study will be difficult to apply to other team sport settings (e.g age group, competitive standards) as it was undertaken on a homogeneous population (Eys et al, 2003). It has also been reported that greater role ambiguity and role clarity could affect an athletes self efficacy, satisfaction and performance. These factors could not only affect the individual but the team as a whole (Forsyth, 1999). Beauchamp Bray (2001) investigated university athletes perceptions of role ambiguity and role conflict among their respective sports teams. Results demonstrated that members who perceived greater levels of role ambiguity and conflict had lower levels of efficacy and were less inclined to perform their role responsibilities. This is concurrent with Bandura, (1997) who suggested a decrease in persistence and effort will occur if the athlete is unclear of their role. The associated performance is also likely to suffer (Bandura, 1997) as indicated by Beauchamp et al, (2002) who found a negative relationship between role efficacy and role performance. Additionally, the relationship between leadership and role ambiguity could prove further understanding of thi s subject (Eys et al, 2003). The more detailed, specific and challenging yet realistic a goal is the more effective it will be (Gould, 1993). However, research found team members often set themselves unclear and generally descriptive goals (Brawley et al, 1992). In addition, when Dawson et al, (2002) interviewed varsity athletes to determine their goal setting habits, they found team members set personal goals and their respective teams had group goals. Research has indicated that team as opposed to individual goals are better for improving team sport performance (Johnson et al, 1997). The authors demonstrated how subjects who set team goals improved their bowling performance in cricket, yet subjects who set personal goals did not. The addition of team goals to a group has proven successful in the past. Lee (1988) found that adding team goals to female hockey teams had a positive effect on team performance. This was concurrent with Senecal et als, (2008) study of female basketball players. Over a season long intervention, they found team cohesion significantly increased in the intervention group compared to the control groups when they utilised team goal setting. Furthermore, Mellalieu et al. (2006) found a goal setting program with professional rugby players to have a positive impact on performance. It has been suggested that goal setting can enhance team cohesion by providing a team focus (Widemeyer Ducharme, 1997). Focusing on one goal can improve group communication, commitment and satisfaction, improving group cohesion and subsequent performance (Carron Spink, 1993) Nevertheless, there have not been many studies carried out in sport that have investigated the effect of team goals on team performance (Widemeyer Ducharme, 1997), with the majority of studies conducted outside of the sport setting (Weingart, 1992). Team building intervention A team goal setting program was chosen as the intervention topic to improve team cohesion (see appendix a). Early research from Widemeyer et al, (1992), as cited in Widemeyer Ducharme (1997) found athletes felt having a team goal was the most significant contributor to task cohesion from a choice of 35 variables. More recently, Stevens Bloom (2003) found team goals to be the most effective topic to utilise in a team building intervention. The following team building intervention applied principles from Eys et al, (2006) in Senecal et al. (2008), Widemeyer Ducharme, (1997) and Widemyer McGuire, (1996) in Carron et al, (2005). Step 1: Developing Long term goals Firstly, the athletes and coaches will work together to decide the long term goal of the team (Kyllo Landers, 1995) for example, achieve a top 3 position in the league. This will take place during an all day workshop during the first week of pre season. The athletes will work in small sub groups of 3-4 and discuss long team goals for the team (Eys et al, 2005). Once the sub groups have decided a long term goal, the coach will write the goals on the white board and the team will discuss together (Dale Wrisberg, 1996), narrowing down to one specific and measurable goal (Gould, 1993). The Long term goal will then be posted in the changing rooms for the remainder of the season, to help motivate the athletes (Weldon Weingart, 1988). Step 2: developing short term outcome goals To achieve the long term goal, specific and measurable (Carron et al, 2005) short term goals will be set as stepping stones (Kingston Hardy, 1997), for example, win the next 3 out of 5 games. To decide the goals, the coach will remind the players of last seasons statistics (eg. Wins, losses, league position) (Widemeyer Ducharme, 1997). After the long term goals are decided, the players will use these statistics and repeat the same procedure as in step 1 by getting into subgroups (Eys et al, 2005). Once discussed, 5-6 specific and achievable short term outcome goals will be decided (Widemeyer Mcguire, 1996) Step 3: Developing short term performance goals In addition, the players will set performance goals during a second all day workshop, 2 weeks into the pre season. The use of multiple goal setting strategies has been shown to be more beneficial to performance (Filby et al, 1999). For this intervention, the players will only be working towards team goals as previous research has suggested team goals are better for improving team performance (Johnson et al, 1997) and that individually hidden goals have no significant impact on performance (Kyllo Landers, 1995). The performance goals will be decided through the use of performance profiling (Dale Wrisberg, 1996). This will be a group profile for the team as a whole. Firstly, the players will discuss what characteristics they believe a successful football team has. The players will express their opinions to the coach while they write them down onto a white board. The characteristics will need to be specific, so if there too general they will be re-evaluated until clearer. When the athletes and coach are happy that at least ten appropriate characteristics are on the white board, the players will individually and anonymously write all the characteristics off the white board on to paper. Examples of characteristics could be; putting 100% effort into every training session and game, winning over 80% of their aerial battles. The players will then proceed to evaluate their teams characteristics between a scale of 1-10, with 1 being weak and 10 being strong. Once completed, each characteristic will be calculated as a mean. The lowest mean scores will be the areas developed into performance goals that the team will aim to achieve. Additionally, the coach will use the same procedure to demonstrate their perceptions of the team. At the next group meeting the team will discuss the results (lowest scores) and agree on 5-6 performance goals to improve their perceived weaknesses (Dale Wrisberg, 1996). When the specific performances goals are established, the team needs to decide realistic yet challenging target levels for these goals (eg. more than 5 shots on target per game) (Carron et al, 2005). To make sure their realistic and challenging the coach will again provide the athletes with statistics from last season (eg. shots on goal, tackles won). The sub group procedure used in step 1 and 2 will be utilized to achieve this (Eys et al, 2005). After negotiations the team will conclude the appropriate targets for their team. This process will be repeated during the middle and the end point of the competitive calendar (Dale Wrisberg, 1996) so that the performance goals can be updated throughout the season Step 4: Monitoring and evaluation of short and long term goals The Long and short term goals will be continually monitored throughout the intervention. Prior to every match and practice session (1 of each per week) throughout the pre and competitive season the team will be reminded of the goals they set for themselves in attempt to provide a focus for the team and help motivate the players (Weldon Weingart, 1988). To do this team goals will be written on the white board in the changing rooms, the coach will then highlight the importance of these goals during their team talk. In addition, after each match team statistics (eg. goals scored and corners won in that game) and the statistics for the agreed performance indices will be posted in the changing rooms. The team members can then look at the statistics and measure their progress towards their target levels. Step 5: Updating team goals After every 3-5 games, the coach and players will work with the intervention specialist on evaluating and possibly updating the team goals if needed, eg. Removing or adding performance goals and changing the target level (Senecal et al, 2008). This will be achieved using their performance statistics from the previous 3-5 games and the characteristics of their next 3-5 opponents (Widemeyer McGuire, 1996). Again, the procedure demonstrated in step 1 will be used to administer the changes. Stage 6: Praise continued progress toward team goals During the intervention the coach will continually openly praise his team when they do well and progress toward their team goals, feedback on goal progress may enhance the use of team goals (Widemeyer Ducharme, 1997). Step 7: post intervention check. 1 week after the intervention was completed; A 5 question, post intervention questionnaire (Stevens Bloom, 2002) was completed by every player to assess the effectiveness of the intervention (Senecal et al, 2008). In addition, 1 and 3 months after the intervention is completed interviews will be conducted with each player (Stevens Bloom, 2003). Players will be instructed to relax and openly discuss their opinions of the TBIs effectiveness. Critical analysis of team building interventions in sport Team building interventions are designed to improve group performance by increasing group cohesiveness (Carron et al, 1997). However previous studies have produced mixed results on the effectiveness of team building interventions (TBI) on improving cohesion. Some were effective (Voight Callaghan, 2001; Senecal et al, 2008; McClure Foster 1991; Mellalieu et al, 2006) and some were unsuccessful (Prapavessis et al, 1996; Cogan Petrie, 1996; Stevens Bloom, 2002). One study, Steven Bloom (2003) found their TBI to be effective during the pre season but not throughout the competitive season. Nevertheless, Brawley Paskevich (1997) have highlighted many methodological concerns with the research conducted using team building interventions. For example, the pre-test, post-test experimental design employed by various TBI (Voight Callaghan 2001: Senecal et al, 2008; Prapevessis et al, 1996; Stevens Bloom, 2002; Mellalieu et al, 2006) makes it difficult to determine the effectiveness of the intervention. Although three of these studies were effective (Voight Callaghan 2001: Senecal et al, 2008; Mellalieu et al, 2006), due to the absence of measures throughout the competitive season, although likely it makes it difficult to determine whether or not it was the TBI that improved performance or outside interference, questioning the validity of their results. For example, Brawley Paskevich, (1997) suggested leadership change; a less competitive calendar or the loss of an unsettling member could have all influenced team cohesion independent of the TBI. Some studies that employed a quasi experimental design (Cogan Petrie, 1996; Stevens Bloom, 2003) reported their TBI to be ineffective at improving team cohesion. The design could be the reason for their lack of significant results. A quasi experimental design rarely includes random assignment making it difficult to determine whether factors such as differences in coaching style and team atmosphere affected the results (Stevens Bloom, 2003). Randomly assigning members to different teams, allows experimenters to observe which treatment of the TBI infers change (Brawley Paskevich, 1997). One study employed an experimental design (Mclure Foster, 1991). The results of their study suggested their intervention was effective at increasing cohesion among gymnasts. The positive results of their study could be attributed to the experimental design as this method includes random assignment. Therefore they were able to notice a difference in cohesion amongst randomly assigned athletes with out interference from some of the problems mentioned above. Furthermore, some studies did not utilise a control group, one was effective at improving cohesion (Voight Callaghan 2001) another was ineffective (Bloom Stevens 2002). The absence of a control group however, questions the validity of Voight Callaghans (2001) results. As suggested by Brawley Paskevich, (1997) it is difficult to establish whether their TBI was actually the cause for the improvement in performance as there were no control or placebo groups to compare the results to. In addition, as Stevens Bloom (2002) did not include a control group, whether or not cohesion levels would have decreased over the season and therefore whether or not the intervention was helpful to the team is unclear. Additionally, the duration of the TBI is another methodological concern identified by Brawley Paskevich (1997). It has been suggested interventions are fairly slow processes (French Bell, 1984) and at least 1 season of a TBI is needed to produce results of any significance (Brawley Paskevich, 1997). Therefore the results of studies that lasted less than a season (Prapavessis et al, 1996; Mellalieu et al, 2006) may not portray the long-term effects of the intervention. Studies that have lasted at least a season (Senecal et al, 2008; Mclure Foster 1991; Stevens Bloom, 2002; Voight Callaghan, 2001; Stevens Bloom, 2003; Cogan Petrie, 1996) are more likely to provide clearer results. In addition, although the vast majority some of these studies administered post intervention checks (Cogan Petrie, 1996; Senecal et al, 2008; Mellalieu et al, 2006; Stevens Bloom; Voight Callaghan, 2001; Prapevessis et al, 1996; Stevens Bloom, 2002) none of these studies administered any questionn aires 3 or 6 months after the intervention to examine the long term effects of their intervention. Sampling size can be another methodological concern for researches conducting TBIs. Two studies had a very small sample size (Mellalieu et al, 2006: 5 participants; McClure Foster, 1991:15 participants. Some studies have only used a slightly larger sized sample consisting of no more than 45 participants (Cogan Petrie, 1996; Voight Callaghan, 2001; Stevens Bloom, 2003; Stevens Bloom, 2002). Only 2 studies have used relatively large sample sizes: Senecal et al, (2008); (n=86) Prappevessis et al, (1996); (n=137). Nevertheless, all studies have reported sufficient details such as gender, age, sport and team ability (Cogan Petrie, 1996; Voight Callaghan, 2001; Stevens Bloom, 2003; Stevens Bloom, 2002; McClure Foster, 1991; Mellalieu et al, 2006; Senecal et al, 2008; Prapavessis et al, 1996) However, some of the characteristics reported in the studies can be vague. Many studies have failed to state appropriate details, such as race (Voight Callaghan, 2001; Prapevessis et al, 199 6; Senecal et al, 2008; McClure Foster, 1991; Stevens Bloom, 2002; Mellalieu et al, 2006). Furthermore, the majority of studies also seem to be generalized to similar populations. For example, the majority of studies were conducted on females (Voight Callaghan, 2001; Senecal et al, 2008; McClure Foster, 1991; Cogan Petrie, 1996; Steven Bloom, 2003; Stevens Bloom, 2002), on ages ranging between 18-24 (Voight Callaghan, 2001; McClure Foster, 1991; Cogan Petrie, 1996; Steven Bloom, 2003; Mellalieu et al, 2006) and on high school or university teams (Cogan Petrie, 1996; Steven Bloom, 2003; McClure Foster, 1991; Senecal et al, 2008). In addition, the studies that indicated the race of the subjects were predominately on Caucasians (Cogan Petrie, 1996; Steven Bloom, 2003). As these studies are on similar populations the generalizability of these interventions is limited. Therefore, the results are difficult to apply to a wide range of sports teams, as member characteristics s uch as age, gender, race and ability can vary greatly per team. Previous studies on sport teams have had the coach/manager as the main facilitator of the intervention, working with the intervention specialist. As a result, Some TBIs have taken a more indirect approach (Prappevessis et al, 1996) or used a combination of indirect and direct models (Steven Bloom, 2003; Cogan Petrie, 1996; Mellalieu et al, 2006). However, Brawley Paskevich (1997) identified indirect models to have weaknesses. The authors explain that coaches/managers may not be capable of undertaking a TBI as they do not have the knowledge, time and commitment to make it successful. On the other hand, direct models have the advantage of often allowing the intervention specialist to work directly with the participants. In addition, the team members become more involved in the decision making process during the intervention. Bloom, (1996), suggested the involvement of the athletes is a key factor in improving team performance. From the four studies reviewed that utilised a direct te am building model, 3 were effective at improving cohesion (Senecal et al, 2008; Voight Callaghan 2001; McClure Foster, 1991) with only one unsuccessful (Stevens Bloom, 2003). References Bandura, A. (1997). Self-efficacy: The exercise of control. New York: Freeman. Beauchamp, M. R., Bray, S. R. (2001). â€Å"Role ambiguity and role conflict within interdependent teams†. Small Group Research, 32, 133-157. Beauchamp, M. R., Bray, S. R., Eys, M. A.,Carron, A. V. (2002). â€Å"Role ambiguity, role efficacy, and role performance: Multidimensional and mediational relationships within interdependent sport teams†. Group Dynamics: Theory, Research, and Practice, 6, 229-242. Bloom, G. A. (1996). Life at the top: Philosophies of success. In J. H. Salmela (Ed.), Great job coach! Getting the edge from proven winners (pp. 37-65). Ottawa, ON: Potentium. Bloom, G.A. and Stevens, D.E. (2002). â€Å"Case study: A team-building mental skills training program with an intercollegiate Equestrian Team†. Athletic Insight 4, The Online Journal of Sport Psychology Brawley, L.R., Carron, A.V. Widmeyer, W.N. (1992). â€Å"The nature of group goals in sport teams: A phenomenological approach†. The Sport Psychologist, 6, pp323-333. Carron, A.V., Spink, K.S. (1993). Team building in an exercise setting. The Sport Psychologist, 7, 8-18. Carron, A.V., Spink, K.S., Prapavessis, H. (1997). â€Å"Team building and cohesiveness in the sport and exercise setting: Use of indirect interventions†. Journal of Applied Sport Psychology, 9, pp61-72. Carron, A.V. and Hausenblas, H. A., Eys, M.(2005). Group dynamics in sport. Morgantown, WV: Fitness Information Technology. Cogan, K.D. and Petrie, T.A. (1996). â€Å"Sport consultation: An evaluation of a season-long intervention with female collegiate gymnasts†. The Sport Psychologist, 9, pp282-296. Dale, G.A. Wrisberg,, C.A. (1996). â€Å"The use of a performance profiling technique in a team setting; Getting the athletes and coach on the same page†. The Sport Psychologist, 10, pp261-277. Dawson, K. A., Bray, S. R., Widemeyer, W. N. (2002) â€Å"Goal setting by female intercollegiate sport teams and athletes, Avante, 8, pp14-23 Eys, M. A., Carron, A. V. (2001). â€Å"Role ambiguity, task cohesion, and task self-efficacy. Small Group Research, 32, 356-373. Eys, M. A., Carron, A. V., Beauchamp, M. R., Bray, S. R. (2003). â€Å"Role ambiguity in sport teams†. Journal of Sport and Exercise Psychology, 25(4), 534-550. Forsyth, D. R. (1999). Group dynamics (3rd ed.). Belmont, CA: Wadsworth Eys, M, A., Patterson, M. M., Loughead, T. M., Carron , A. V. (2005) â€Å"Team building in sport†. In Hackfort, D., Duda, J. L., Lidor, R., Handbook of Research in Applied Sport Psychology: International Perspectives (pp219-233). Morgantown, WV: Fitness Information Technology Eys, M. A., Loughead, T. M., Hardy, J. (2007) â€Å"Athlete leadership dispersion and satisfaction in interactive sport teams†, Psychology of Sport and Exercise, 8, pp281-296 Filby, W. C., Maynard, I. W., Graydon, J. K. (1999) â€Å"The effect of multiple goal strategies on performance outcomes in training and competition. Journal of Applied Sport Psychology, 11, pp230-246 French, W.D. Bell. C.H. (1984). Organization development: Behavioural science interventions for organization improvement (3rd Ed). Englewood Cliffs, NJ: Rentice-Hall. Gould, D. (1993). Goal setting for peak performance (2nd ed.).Mountain View, CA: Mayfield Publishing Company Johnson, S. R. Ostrow, A. C., Perna, F. M., Etzel, E, F. (1997) â€Å"The effects of group versus individual goal setting on bowling performance. The Sport Psychologist, 11, pp190-200. Kingston Hardy (1997). â€Å"Effect of different types of goals on processes that support performance†. The Sport Psychologist, 11, pp277 293. Kyllo, L. B., Landers, D. M. (1995) â€Å"Goal setting in sport and exercise: A research synthesis to resolve the controversy†. Journal of Sport and Exercise Psychology, 17, pp117-137 Lee, C. (1988). â€Å"The relationship between goal setting, self-efficacy, and female field hockey team performance†. International Journal of Sport Psychology, 20, pp147- I61 Lee, H. K., Kim, B.H., Lim, B. H.(1993) â€Å"The influence of structural characteristics of team success in sports†, Korean Journal of Sport Science, 5, pp138-154 Loughead, T. M., Hardy, J. (2005). A comparison of coach and peer leader behaviours in sport. Psychology of Sport and Exercise, 6, 303-312. Loughead, T. M., Hardy, J., Eys, M. A. (2006). The nature of athlete leadership. Journal of Sport Behaviour, 29, 142-158. McClure, B. Foster, C.D. (1991). â€Å"Groupwork as a method of promoting cohesiveness within a womens gymnastics team†. Perceptual and Motor Skills, 73, pp307-313. Mellalieu, S.D., Hanton, S., OBrien, M. (2006). The effects of goal setting on rugby performance. Journal of Applied Behavior Analysis, 39, pp259 261. Prapavessis, H., Carron, A.V. Spink, K.S. (1996). â€Å"Team building in sport†. International Journal of Sport Psychology, 27, pp269-285. Riemar, H.A. Chelladurai, P. (1995). Leadership and satisfaction in athletes†. Journal of Sport and Exercise Psychology, 17, pp276-293. Senecal, J., Loughead, T.M. Bloom, G.A. (2008). â€Å"A season-long team-building intervention: Examining the effect of team goal setting on cohesion†. Journal of Sport and Exercise Psychology, 30, pp186 199. Stevens, D.E., Bloom, G.A. (2003). â€Å"The effect of team building on cohesion†. Avante, 9, pp43-54. Voight, M. and Callaghan, J. (2001). â€Å"A team building intervention programme: Application and evaluation with two university soccer teams†. Journal of Sport Behaviour, 24 ,pp420 431. Weldon, E.. Weingart. L.R. (1988). â€Å"A theory of group goals and group performance†. Paper presented at the annual meeting of the Academy of Management. Anaheim, CA. Weingart. L.R. (1992). Impact of group goals, task component complexity, effort, and planning on group performance. Journal of Applied Psychology, 77. 682-693. Westre, K. R. And Weiss, M. R., (1991) â€Å"The relationship between perceived coaching behaviours and group cohesion in high school football teams†, Sport psychologist, 5, pp41-54 Widmeyer. W.N., Silva. J.M. Hardy, C.J. (1992). â€Å"The nature of group cohesion in sport reams: A Phenomenological approach†. Paper presented at the annual meeting Of the Association for the Advancement of Applied Sport Psychology. Colorado Springs, CO. Widemeyer, W. N., McGuire, E, G. (1996) Sport psychology for ice hockey. Presentation to Ontario Intermediate Coaching Clinic, Waterloo; Ontario Widmeyer, W.N. DuCharme, K. (1997). â€Å"Team building through team goal setting†. Journal of Applied Sport Psychology, 9, pp97-113.

Friday, October 25, 2019

Pancreas Transplant: A Cure for Diabetes?” :: Endocrine System

The article, â€Å"Pancreas Transplant: A Cure for Diabetes?† written by Eli A. Friedman, M.D., explores the possibility of a cure for type 1 diabetes and the implications involving this experimental procedure. The article discusses current procedures and treatments that are commonly used to control type 1 diabetes and highlights provisional treatments that evolved into pancreatic transplant surgery. The editorial explains that diabetes mellitus is the leading cause of irreversible renal failure, known more commonly as End Stage Renal Disease (ESRD). Diabetes mellitus can cause nerve, vascular and other problems that can result in limb amputation and blindness. There are two types of diabetes: long-duration, non-insulin dependent (type 2) and insulin-dependent (type 1). Type 1 seems to attract the most attention from Physicians and the media. Many of those that suffer from type 1 are children and young adults. Dr. Friedman underlines some of the most common existing treatments for type 1 diabetes. Insulin is used to correct the imbalances in blood sugar and patients are required to reduce the amount of dietary protein they consume. This type of treatment focuses on slowing the possibility of developing kidney disease and retinopathy. For many diabetics, the time will come when their damaged kidneys are no longer sufficiently cleaning the blood and they must begin dialysis. When a diabetic reaches the ESRD stage, the likely option is kidney transplant. Dr. Friedman adds that a kidney transplant will not solve the problem and the disease will eventually progress without a pancreas transplant. The article stipulates that diabetes involves the pancreas as well as the kidney. The pancreas produces insulin, the hormone that regulates glucose. When the pancreas malfunctions, diabetes can result. The idea behind kidney/pancreas transplant is to replace the kidneys damaged by diabetes and to eliminate abnormal insulin production by providing a new healthy pancreas.

Thursday, October 24, 2019

Development of Anti-Idiotype Vaccine for Human Follicular Lymphoma

Non-Hodgkin’s lymphomas (NHL) constitute a heterogeneous group of malignancies whose incidence has significantly increased in recent decades. In the year 2000, more than 145,000 cases of NHL were diagnosed in developed countries, representing thus the sixth most common cancer occurring among men and the eighth among women. Low-grade B-cell NHLs, in particular, are incurable diseases characterized by relatively slow growth and excellent initial responsiveness to chemotherapy but also by continuous relapses. In particular, for patients with follicular lymphoma, median overall survival (7-10 years) has not improved over the past 30 years. Although in the vast majority of patients complete or partial remissions can be obtained with either single agents or combination chemotherapy, the clinical course is characterized by a high relapse rate. After relapse, both the response rate and relapse-free survival after subsequent salvage treatment regimens steadily decrease, resulting in a median survival of only 4-5 years after the first relapse. These clinical findings, coupled with the substantial toxicities of standard treatments, have stimulated the search for novel and more tumor-selective therapies.Follicular lymphoma is a clonal B cell malignancy that expresses a unique antigen that is formed by the immunoglobulin light and heavy chains that possess highly variable regions at their amino termini. These variable regions combine to form the antigen recognition site, which can itself be recognized as an antigen, termed the idiotype. The antigen-binding site is a structural feature of each immunoglobulin that distinguishes it from other immunoglobulins. The idiotype of a particular clonal B cell lymphoma represents a tumor-specific antigen. Idiotype is a target of interest in human lymphoma.Therapeutic vaccines targeting B cell lymphoma idiotype (Id) represent a promising immunotherapeutic approach for a better clinical control of these malignancies.Immunoglobulin (Ig) molecules are composed of heavy and light chains that possess highly variable regions at their amino termini. B-cell malignancies are clonal proliferations of Ig-producing cells. The idiotypic determinants of the surface Ig can thus serve as a tumor-specific marker for the malignant clone.Indeed, both protein- and dendritic cell-based vaccines that use the patient-specific Id have resulted in clinically significant tumor-specific cellular responses with very little toxicity. A broad use of Id-based vaccination for B cell lymphomas, however, is hampered by the fact that these approaches are patient-specific so that the vaccine must be individually produced for each patient. On these grounds, new strategies obviating the need to produce customized vaccines would further simplify clinical applications of idiotypic vaccines.Goals:Goal 1:Establishment of a large database including sequences of idiotypic VH and VL genes expressed by a variety of lymphoproliferative disorders, includ ing low grade B-NHL, autoimmunity-associated lymphoproliferations, and chronic lymphocytic leukemia. This will allow the identification of candidate Id proteins for â€Å"cross-reactive† immunotherapy.Goal 2:Pre-clinical characterization of the immunogenicity of selected natural Id proteins, with particular regard to their ability to induce immune responses against lymphoma cells expressing molecularly correlated Id proteins. The characterization will include the identification of B cell epitopes and HLA Class I-restricted cytotoxic T cell epitopes using innovative approaches and will allow the development of dedicated assays for immunomonitoring.Goal 3:Design and validation of optimized Id vaccine.Goal 4:Evaluation and validation of new adjuvants and innovative delivery systems for improved Id vaccine formulations and administration.Goal 5:â€Å"Clinical-grade† production and purification of optimized Id proteins for patient vaccination.IntroductionThere are approxima tely 65,000 new cases of non-Hodgkin’s lymphoma diagnosed each year in the US with a comparable number in Europe. Despite the use of aggressive chemotherapy and recent advances in therapy such as monoclonal antibodies (Rituxan, TM), the disease is almost invariably fatal. Follicular lymphoma (FL) patients, in particular, can have an indolent but ultimately fatal clinical course. The median relapse time for FL patients is three years, with 90% of patients dying of a tumor-related mortality within 7 years of the date of diagnosis.The clinical course is usually characterized by a series of remissions and relapses. Good response rates are seen with treatments such as chemotherapy, radiation, lymphocyte transplantation, and monoclonal antibodies. However, following initial response to treatment, the cancer invariably returns and the majority of patients relapse with resistance to all available therapy. Related B-cell derived neoplasms include multiple myeloma (approx. 15,000 cases /year in the US and chronic lymphocytic leukemia (approx. 10,000 cases/year in the US).Isolation of tumor-specific antigens (TSAs) has been a long sought-after goal for scientists involved in both basic and clinical research. Whereas tumor-associated antigens (TAAs) are localized on both normal and tumor cells, TSA are peculiar to tumor cells. This characteristic makes TSA a very desirable target for immune therapy strategies aiming to spare normal cells, or at least the indispensable ones.As regards effectors mechanisms, although some indirect evidence exists for participation of both natural killer (NK) cells (especially those activated by IL-2, known as lymphokine- activated killer, or LAK cells), and TNF-secreting macrophages in tumor immunity, most interest has been focused on the role of antigen-specific antibodies and T lymphocytes. This is particularly true among scientists developing anti-Id vaccines for human FL, even though no substantial agreement has yet been reached on which of the two main effectors pathways is most important.FL conforms to the general rule that tumors have several mechanisms to escape the attention of the immune system. The risks that Ig somatic hypermutations could result in aminoacid residue replacements leading to substantial changes within the fine immunogenic structure of the Id do not seem to be so relevant. Indeed, no such occurrence has been reported in any of the several dozen patients who have been immunized over the last decade. A much more relevant issue is the very limited ability of FL cells to present their own antigens.Although ontogenetically very close to normal mature B-lymphocytes, with respect to their normal counterparts FL cells are very poor as antigen presenting cells (APCs). This makes it rather difficult to evaluate any vaccine-induced, tumor-specific cytotoxicity even in vitro. On the other hand, no such problems exist for ELISA-based detection of the tumor-specific and vaccine-induced humoral respon se.The first study of anti-Id vaccinations in humans dates only from 1992. Until then, all the work had obviously been confined to animal models. However, the accumulation of experimental data has led to the development of several promising strategies that are currently being investigated in clinical trials. These include the utilization of the Id in the form of a soluble protein or as a DNA sequence, either used to pulse dendritic cells (DCs) or else to be administered in combination with immunologic adjuvants.Soluble protein Id vaccine production is based on a hybridoma technique, which in vitro allows production of exactly the same Ig as that present on the surface of the clonal B cells of FL, or in other words the tumor-specific Id. The suspension of single cells obtained from a biopsy specimen almost invariably contains a residual population of normal B-lymphocytes alongside the tumor cells. Screening of the hybridomas by means of Ig heavy chain CDR3 PCR identification is there fore required in order to make sure that the Ig of the selected hybridoma is truly identical to the tumor- associated one.31 Once the cultured hybridoma has yielded enough purified Id, the TSA needs to be made far more immunogenic than it is in its free form. For this purpose, it may either be conjugated with a highly immunogenic carrier such as keyhole limpet hemocyanin (KLH), or else used to pulse autologous DCs.The association of a soluble protein Id vaccine with immunologic adjuvants monocyte colony-stimulating-has also proved extremely important. Granulocyte factor (GM-CSF) currently seems to be the best such adjuvant both in animal models and humans, probably because of its capacity for local recruitment of DCs in vivo at the site of vaccine injections. This step would appear to be superfluous when autologous DCs are loaded with Id ex vivo and then re-injected into the patient.A completely different alternative approach involves administration of the patients’ Id-encodi ng DNA sequence. With the rise of molecular technology, such DNA vaccines are beginning to come into their own. For instance, exploitation of appropriate molecular vectors (ie containing both a leader and promoter sequence) for insertion of the nucleotide sequences responsible for biosynthesis of both the Ig heavy and light chains variable regions is now relatively easy.Between the heavy- and light-chains variable regions sequences, an intertwined linker peptide must also be inserted to allow the ultimate Id-containing molecule (scFv) to fold properly. Furthermore, the vaccine can be further strengthened by adding other DNA sequences encoding for immunologic adjuvants or powerful immunogens to the vector. Finally, intramuscular injections allow progressive release of the Id following synthesis by muscular cells. In addition, this administration route seems to be associated with prolonged conservation of the genetic information within the cells without any apparent signs of integrati on into their genome.Experimental DesignGoal 1:Establishment of a large database including sequences of idiotypic VH and VL genes expressed by a variety of lymphoproliferative disorders, including low grade B-NHL, autoimmunity-associated lymphoproliferations, and chronic lymphocytic leukemia. This will allow the identification of candidate Id proteins for â€Å"cross-reactive† immunotherapy.In establishing a database, there will be steps to follow in order to support the evidences claimed.I. Finding the cases and the occurrence of VH and VL in lymphoproliferative disorders in different hospitals and institutions that could provide valuable information for the said disorders. The facts and information should have the confirmed consent of the persons involved.II. Subjecting the cases to thorough analysis to provide the essential information needed in documenting the cases.III.   Testing the subject under the identification of Id proteins.IV. Organizing the information and est ablishing the database.Methods:Establishing a database to easily organize information and data needed in making the information available readily whenever they will analyze situation in which there is a suspected occurrence of lymphoproliferative disorder. By providing the information needed, they could develop system that would make things easier for them to do actions required in addressing such situation.Primary step is consolidating all the available facts and information provided that they have the consent from the owner of the information. By having the desired facts available for the reorganization of it, they could classify it according to the general category they want to use in creating their database. It could be based on severity of the case or could be base on gender or any factor that could greatly affect the situation.Then, by gathering the information they needed, the analysis of the data should be carefully done for them to eliminate excess and negligible data for a n easier organization of the structure of their available resources. By implicating the main thrust of the database to the core concept of having advance cases of NHL, the higher chance they could get the information and the data based on the clinical findings of actual patients and people who suffered from that.By simply opening the way of introducing different vaccines in addressing the situation, they could develop a system of transferring and managing information that could make things easier especially in developing new technology and medicinal advancement in creating a better and more effective ways of treating such disease. By making the information more manageable, they could likely innovate an advance communication that would lead them in establishing better information and data management for the use of the development of vaccines and cures.Since they have the information but they should examine carefully every bit of information that will be a part of their set of data an d facts. By looking closely to the subjects result and the specification of the action done, the development of such process in introducing a new finding on the matter should be considered. Since the goal is to establish a database that will focus on the information that could provide the facts needed on the cases diagnosed with a NHL, it is important to screen the cases as important and not negligible for them to be able to use it as a case.At the end of the process, they would go back to their primary goal and that is to establish a functional database that the core information and the key factors are integrated in a way that it would make the processing of facts and vital data would be efficient and effectively handled.Also, it will introduce technology that would compensate the fast rising of development in technological advancement even in the field of medicine. Because there are ready to use valuable information for them to handle and initialize their desired action, they woul d be able to commend the different opportunities in which they could get specimens and studied it for future discoveries and researches.In all, by their incorporation of the cases of NHL and their desired goal of making the information available for them to be able to easily study and review the situations and cases they previously have for them to execute and evaluate the validity of the existing tests in the current occurrence of the disease in the real place.Goal 2:Pre-clinical characterization of the immunogenicity of selected natural Id proteins, with particular regard to their ability to induce immune responses against lymphoma cells expressing molecularly correlated Id proteins. The characterization will include the identification of B cell epitopes and HLA Class I-restricted cytotoxic T cell epitopes using innovative approaches and will allow the development of dedicated assays for immunomonitoring.In dealing with the pre-classification of the immunogenicity of selected natu ral Id proteins, the processes involved are:I.   Accumulating soluble proteins to be tested.II. Testing them with hybridoma essential in testing the equivalence of the tumor inducing material that leads to development of the tumor.III.   Inducing the effect of the proteins and identifying its effect on B cells.IV. Using advance technique in analyzing the result and implicating with the use of the modern testing equipment and processes.Accumulation:Testing the proteins for it to be classified will be the first step. From the patients who are suffering from FL, different samples will be getting for the medical technology to be applied. Then by cultivating natural proteins, they will use it to further test the capacity of the natural cell in penetrating and deeply interacting with other Id proteins in the development of resistance to such substance.By eradicating some external factors such as the presence of other organisms, they could screen the protein level for them to be able t o produce and test the Id proteins by exposing it to toxoids that could develop resistance on the desired solution. Then, the Id proteins gathered will be stored for further testing.Testing:Then, preparation of the Id protein to be tested will be carefully done in a controlled environment. Since the tumor development can not be detected by the immune system, the development of inducing material will be necessary for them to penetrate the basic defenses of the tumor.By exposing it to NKL, tumor will exhibit a different behavior but will not be extinguished. Since B cells epitope derived multiply myeloma that had been the major cause of the return of the behavior of the tumor cells, the gradual exposing it to be classified by soluble Id proteins will be dedicated.The allowance of certain percent productivity will be the basic goal of the clinical testing for them to be able to derive the pre-classification scheme that will determine substances that induce immunity on certain level wit h the use of soluble and Id protein present in the environment.Effect and its IdentificationAfter the testing had been carefully done, they will examine its effect on various elemental positions by trying the substance on the possible outcome. Then, FL cells will be isolated then proteins will be added to see the effect on the neoplasms produced by B-cells. Since the outcome would produce certain behavior that will exhibit a different expected one, the process will be repeatedly associated with soluble proteins to target the development of TSA since it target tumor cells.Analyzing the ResultThen, the result will be analyzed in a way that it consistently produces same output. Then after looking closely and making sure that no other substance induced the effect, the validity of the result will be the next concern in analyzing the data. For it to be valuabe, the result should consist the scientific analysis of the vaccine to be introduced for them to be able to adopt a real one.Goal 3: Design and validation of optimized Id vaccine.Since the protein had been introduced in TSA that would target tumor cells, it is important to develop the next stage wherein it will pay attention to that. Tumor cells, after being extinguished by some other methods, always come back and provide a worse situation that before. It is a common problem of the development of cure because as soon as they introduce stronger antigens and antibiotics, the cells develop stronger immunity to them, making them more powerful and gave them the power to come back and come back whenever they are defeated.The result of the previous testing of the material will be used as the raw data in determining the precise development of the vaccine needed for the tumor cells. Toxoids produced by microorganisms will be introduced to the tumor cells for them to create an astounding reaction with the cells to help the antigens produce a better shield to the tumor cells.They would also address the production of its own immunity by targeting the B cells epitopes produced by the tumor cells for them to be able to weaken the effect of the tumor cells in the body. By simply having the same effect on the cells, they would establish the immunity desired.In addition, since soluble proteins produces amino acid residue, the effect of it to the development of various outgoing tumor cells will be beneficial in the sense that it would catch up the screening proves by a hard core stimulation of heavy chain CDR3 PCR. Then, the use of material that would likely predict the behavior will also introduce for the existing antigen to determine it.Goal 4:Evaluation and validation of new adjuvants and innovative delivery systems for improved Id vaccine formulations and administration.After having the result of the vaccine being tested hand-on on the tumor cells, the activation of the production of antigens will be manipulated for those to be able manage the outcome of the result. By having the systematic chain of micr o toxoids that will enter the entire system of the body, they would likely produce different kinds of reactions that would benefit the production of self stimulating antigens.By exposing it to different procedures that would attest the certainty and validity of the desired production, after introducing different sets of toxoids and NK cells, the development of the self inducing multiple protein will help in eradicating the symptoms and the effect of FL.It is known that FL is fatal in terms of its effect on the human entire system. So it is important to devise a precise way of handling and dealing with it for them to be able to have an outer perspective of the natural phenomena.Id proteins will act as binders to the solutions that will be used in strengthening NK cells and TSA to promote the development and inhibit the further production of malignant development of tumor cells. By preventing the further growth of it, they would have larger revenue in which they could satisfy the need s and the improvement for having a stronger antigen.Then, natural growth of TSA will be affected by the inducing of soluble protein to target dendritic cells for them to be able to manifest the basic function of fighting foreign toxins that could affect the development of the tumor as a vital implication of the vaccine. The use of different methods in determining the feasibility of inducing the growth and the development of natural antigens that would be sufficient enough to fight the invading tumor cells will be of great use for them to be able t produce more antigens that will prevent the further worsening of the situation.Validating the use f the vaccine as one of the potential sources of defense against the foreign material invading the system would be beneficial if the could handle the needs of having a more systematized and organized level of founding a solution that would focus on the elimination of cell processes that inhibits the growth of malignant tumor like FL that is fa tal to humans.Subjecting enough NK cells to further strengthening process will help them in making the process worthwhile I making a protein Id that would address the situation as founding solution to the antigen development.Goal 5:â€Å"Clinical-grade† production and purification of optimized Id proteins for patient vaccination.After developing the vaccine the process would involve the following:I.   Purifying the Vaccine to be prepared.II.   Final VerificationIII. Mass ProductionIV.   Patient VaccinationPurificationAfter devising the vaccine, the next step is purifying it by eliminating microorganisms that would have effects on the vaccine. By continuously subjecting the vaccine into different microorganism killing environment, they would lessen the potential of having such. Radiating and constantly developing processes will be sufficient in terminating such microorganisms.Final VerificationAfter the purification of the vaccine, a method will be done for them o be abl e to test if the results are really valid by having it tested for final verification. It is important to deal with it because the importance f verifying the vaccine would greatly affects its validity in the medical society. By having it tested trough lab rats or animals that have developed FL tumors; they would be injected with such vaccine for them to see if the previous results will e the same.Mass ProductionAfter the verification process, the next process will involve producing the vaccine enough for human consumption. The proteins that deal with the development of TSA would have a various report on it validity and essentialism for them to be able to have a developed system of introducing vaccines.VaccinationAfter the production and the vaccine is ready to use, it would be given to the patients, as long as it is approved by the medical board, to be sued as vaccine against the development of FL into malignant tumors that endangered the lives of many people. Then, by having the sys tem of production of certain involvement of the NK cells within the hybridoma of dendritic cells, the vaccine will be of much use since it will introduce antigens that will prepare the body for the possible FL development.Since there are certain kinds of toxoids that will be introduced, there will be a harsh reaction at first to the place where it is injected because of the behavior of the toxoids and the T cells of the body. This is a sign that the vaccine is effective and doing a reaction that would strengthen the immune system of the body.DiscussionAfter the development of the vaccine in FL, it is important to understand the need of developing such because of its adverse effect on the development of humans. It endangered the lives of many people without having the prior notification of the said disease. This is a vital step in the clinical world.Considering the existence of the natural antigens present in the environment, by the use of Id proteins that inhibits the growth of tumo r cells; it would be beneficial to mankind if the continuous development will take place. By exploring the kind of the interaction ventured in this kind of process, the elemental composition of the vaccine would be developed to address the needs of the people in having the desired implication of the subject process.The processing of vaccine would include the development of stages in which it would acknowledge the presence of the cells responsible for the development of the disease. In effect, they would have a better understanding on the subject, matter and would increase the possibility of having a curable state.By implicating the notion of having a different technique in addressing the development of the vaccine, the question left for it is how long would it last for them not only to develop vaccine but also to develop a cure that would forever block the negative effects of the disease. By using and ensuring the safety of the user, they would have a proper citation of the needed p lan for them to be able to execute the importance of the vaccine and its use in the modern life.Furthermore, by examining the application of the vaccine in the curing of the disease, we would see the importance of development and use of innovating techniques in determining the possible outcome of the curing of the disease.Finally, the consideration of the process if it fits the standards of the medical consideration despite the fact that there exist different processes that involve much medicinal advancement should take into consideration the impact of the introduction of this vaccine prior to the ethical understanding of the matter.   Since FL can be considered as one of the deadliest disease that one can have, the help of having a vaccine against it is beneficial to the human industry.

Tuesday, October 22, 2019

Differential police treatment essays

Differential police treatment essays The recent videotaped beating of an African American man in Cincinnati, Ohio by police officers has once again called attention to the volatile relations between police and the African American community. Though this incident is still in its investigation stage, it is merely one in a long history of allegations regarding police misconduct against African American people. For critics, such police conduct includes verbal abuse, unjustified stops and the use of excessive force. Ronald Weitzer (1999) found that according to surveys done by the Bureau of Justice Statistics, police officers have used excessive force in less than 1 percent of contacts with civilians and suspects. Contrary to these statistics, however, blacks perceive excessive force as a problem. A further survey conducted by NBC News found that 43 percent of black respondents had little confidence on the police in the matter of "not using excessive force on suspects" (cited in Weitzer 1999). Definitions of "excessive force" differ from community to community. In two middle-class communities outside of Washington, DC with a majority of black citizens, the practice of "proning out" a suspect on the ground was common during street arrests. This involves putting the individuals on the ground with their arms behind the back. Many black residents charge that individuals are proned out on the ground even when the suspect presents no danger to the officers (Weitzer 1999). In Los Angeles, many members of the African American community feel that they are targeted for more violent police behavior. Often, a suspect who is already proned out was further pinned down with the feet or knees. An amateur video captured an officer with the Los Angeles Police Department slam a black teenager and slam the slender, special-education student on the hood of a car. Later investigations showed that the teenager ha ...